0.2% IVERMECTIN
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Igikorwa cya farumasi
Ivermectinahanini ifite anthelmintic nziza kuri nematode hamwe na arthropods yo hejuru muri vivo.Uburyo bwa anthelmintic nuburyo bwo guteza imbere irekurwa rya acide-aminobutyric (GABA) muri neuron ya presinaptic, bityo igafungura imiyoboro ya chloride ya GABA.Ivermectin nayo ihitamo kandi ihuza cyane imiyoboro ya glutamate-yunganirwa na chloride iherereye hafi y’ahantu h’abunzi ba GABA mu ngirabuzimafatizo z’imitsi n’imitsi, bityo bikabangamira kwanduza ibimenyetso hagati yimitsi ya neuromuscular no kuruhuka no kumugara parasite, bikaviramo gupfa parasite cyangwa kwirukanwa muri umubiri.Inhibitory interneurons na motoneurons ya C. elegans ni urubuga rwabo rwibikorwa, mugihe ikibanza cyibikorwa bya arthropods ari ihuriro rya neuromuscular.Ifite kandi akamaro kurwanya arthropods, nk'isazi y'isazi, mite, na biti.umuntu mukuru Coronaria dentata na parasite zidakuze mu ngurube, nazo zifite akamaro kanini kuri Trichinella spiralis mu mara (zidafite ingaruka kuri trichinella spiralis intramuscular), kandi ikagira n'ingaruka nziza zo kugenzura indwara zamaraso yingurube na Sarcoptes scabiei.Ntabwo ikora kuri trematode na tapeworms.
Imiti ya farumasi
Imiti ya farumasiivermectinzitandukanye cyane bitewe nubwoko bwinyamaswa, imiterere ya dosiye, n'inzira y'ubuyobozi.Bioavailability yo guterwa insimburangingo irenze iy'ubuyobozi bwo mu kanwa, ariko ubuyobozi bwo mu kanwa bwakirwa vuba kuruta gutera inshinge.Nyuma yo kwinjizwa, irashobora gukwirakwizwa neza mubice byinshi, ariko ntibyoroshye kwinjira mumazi yubwonko.Ingano igaragara yo gukwirakwiza mu ntama n'ingurube ni 4,6 na 4 L / kg.Ifite ubuzima burebure mu nyamaswa nyinshi, iminsi 2 kugeza 7 na 0.5 mu ntama n'ingurube.Iki gicuruzwa cyahinduwe mu mwijima, cyane cyane hydroxylated mu ntama, kandi cyane cyane methylated ingurube.Isohoka cyane mumyanda kandi munsi ya 5% isohoka idahindutse cyangwa nka metabolite muminkari.Mu ngomero zonsa, 5% ya dose isohoka mu mata.
Imikoreshereze yibiyobyabwenge
Gukoresha neza hamwe na diethylcarbamazine birashobora kubyara encephalopathie ikabije cyangwa yica.
Igikorwa no gukoresha
Imiti igabanya ubukana bwa Macrolide.Ikoreshwa mukurwanya nematode, acariasis nindwara zudukoko twa parasitike mu ntama ningurube.
Imikoreshereze nubuyobozi
Umunwa: igipimo kimwe, ml 0.1 ku ntama na 0,15 ml ku ngurube kuri kg 1 yuburemere bwumubiri.
Ingaruka mbi
Nta reaction mbi yagaragaye iyo ikoreshejwe ukurikije imikoreshereze ya dosiye.
Kwirinda
(1) Birabujijwe mugihe cyo konsa.
(2) Igomba gukoreshwa witonze mu mbuto mu minsi 45 yambere yo gutwita.
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Igihe cyo gukuramo: iminsi 35 yintama niminsi 28 yingurube.
Igihe cyo gukuramo
Iminsi 35 yintama niminsi 28 yingurube.
Hebei Veyong pharmaceutical Co., Ltd yashinzwe mu 2002, iherereye mu mujyi wa Shijiazhuang, Intara ya Hebei, mu Bushinwa, iruhande rw’umurwa mukuru wa Beijing.Ni ikigo kinini cyemewe na GMP cyemewe n’ibiyobyabwenge, hamwe na R&D, gukora no kugurisha amatungo ya APIs, imyiteguro, ibiryo byateganijwe hamwe ninyongeramusaruro.Nka Centre Tekinike yintara, Veyong yashyizeho uburyo bushya bwa R&D kumiti yubuvuzi bwamatungo, kandi nicyo kigo kizwi cyane mu guhanga udushya mu ikoranabuhanga rishingiye ku buvuzi bw’amatungo, hari abahanga mu bya tekinike 65.Veyong ifite ibishingwe bibiri: Shijiazhuang na Ordos, muri byo ikigo cya Shijiazhuang gifite ubuso bwa m2 78,706 m2, hamwe n’ibicuruzwa 13 bya API birimo Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, n'imirongo 11 yo gutegura harimo gutera inshinge, igisubizo cyo mu kanwa, ifu , premix, bolus, imiti yica udukoko hamwe na disinfectant, ects.Veyong itanga APIs, zirenga 100 bwite- label itegura, na serivisi ya OEM & ODM.
Veyong yita cyane ku micungire ya sisitemu ya EHS (Ibidukikije, Ubuzima & Umutekano), kandi yabonye impamyabumenyi ya ISO14001 na OHSAS18001.Veyong yashyizwe ku rutonde rw’inganda zigenda ziyongera mu Ntara ya Hebei kandi irashobora gutanga ibicuruzwa bikomeza.
Veyong yashyizeho uburyo bwuzuye bwo gucunga neza, yabonye icyemezo cya ISO9001, icyemezo cya GMP mu Bushinwa, icyemezo cya Ositarariya APVMA GMP, icyemezo cya Etiyopiya GMP, icyemezo cya Ivermectin CEP, kandi yatsinze igenzura rya FDA muri Amerika.Veyong ifite itsinda ryumwuga ryo kwiyandikisha, kugurisha na serivisi ya tekiniki, isosiyete yacu imaze kwiringira no gushyigikirwa nabakiriya benshi kubwiza bwibicuruzwa byiza, ubuziranenge bwiza mbere yo kugurisha na nyuma yo kugurisha, gucunga neza na siyansi.Veyong yakoze ubufatanye burambye n’inganda nyinshi zizwi cyane mu bya farumasi y’imiti n’ibicuruzwa byoherezwa mu Burayi, Amerika y'Epfo, Uburasirazuba bwo hagati, Afurika, Aziya, n'ibindi bihugu birenga 60.
