Ivermectin

Ibisobanuro bigufi:

CAS nomero : 70288-86-7

Inzira ya molekulari: C48H74O14

Icyerekezo: Antibiyotike irwanya parasitike

Impamyabumenyi: EU COS, US FDA, GMP, ISO9001

Ibisobanuro: EP, BP, USP

Ibirimo: ≥96%

Ibyiza: Umwanda muke

Icyitegererezo: Birashoboka

Gupakira: 1kg / umufuka wa aluminium.


Ibisobanuro birambuye

Ibiranga ibicuruzwa

Ivermectin

Ivermectinni ifu yera ya kristaline, impumuro nziza.Irashobora gushonga kubuntu muri methanol, Ethanol, acetone, Ethyl acetate, muburyo budashobora gushonga mumazi, hamwe na hygroscopique.Ivermectin ni semisintetike ya macrolide ya antibiyotike igizwe nibice byinshi, irimo cyane cyane ivermectin B1 (Bla + B1b) ibirimo bitarenze 95%, muri byo Bla ikaba itari munsi ya 85%.

ivermectin-drum

Ihame ry'ubuvuzi

Ivermectin igira ingaruka zo guhitamo, muguhuza cyane imiyoboro ya chloride hamwe na glutamate nka valve mumyanya myakura na selile yimitsi yinyamanswa, bigatuma habaho kwiyongera kwimyanya myibarukiro kuri ion ya chloride, bitera hyperpolarisation ya selile nervice. cyangwa ingirangingo z'imitsi, kandi itera ubumuga cyangwa urupfu rwa parasite.Ihuza kandi numuyoboro wa chloride wizindi ligand, nka neurotransmitter g-aminobutyric aside (GABA).Guhitamo ibicuruzwa ni ukubera ko inyamaswa z’inyamabere zimwe zidafite glutamate-chloride muri vivo, kandi avermectin ifitanye isano rito gusa n’inyamabere ya ligand-chloride.Iki gicuruzwa ntigishobora gucengera inzitizi yamaraso yubwonko bwabantu.Onchocerciasis na strongyloidiasis na hookworm, ascaris, Trichuris trichiura, na Enterobius vermicularis.

Gukoresha

Ivermectin ni imiti ikoreshwa mu kuvura ubwoko bwinshi bwa parasite.Ivermectin ikoreshwa mu kuvura indwara zinyamaswa ziterwa ninzoka na ectoparasite.

Ivermectin ikoreshwa muburyo bwo kurwanya inyo za parasitike mu nzira ya gastrointestinal yinyamanswa.Ubusanzwe iyi parasite yinjira mu nyamaswa iyo irisha, ikanyura mu mara, igashyiraho kandi ikuze mu mara, nyuma ikabyara amagi asiga inyamaswa akoresheje ibitonyanga kandi ashobora gutera urwuri rushya.Ivermectin ifite akamaro mukwica bamwe, ariko sibyose, muribi parasite.Mu mbwa isanzwe ikoreshwa nka prophylaxis irwanya umutima.

Mubuvuzi bwamatungo, bukoreshwa mukurinda no kuvura indwara yumutima na acariasis, mubindi bimenyetso.Irashobora gufatwa kumunwa cyangwa gushirwa kuruhu kugirango yanduze hanze.Ivermectin ikoreshwa cyane kuri nematode ya gastrointestinal, ibihaha, na parasitike ya arthropods mu nka, intama, amafarasi, ningurube, nematode yo munda mu mbwa, miti yamatwi, Sarcoptes scabiei, umutima filariae, na microfilariae, na nematode ya gastrointestinal na ectoparasite.


  • Mbere:
  • Ibikurikira:

  • Ibicuruzwa bifitanye isano