250mg Triclabendazole Bolus
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Ibikorwa bya farumasi
Pharmacodynamics Triclobendazole ni iy'ibiyobyabwenge bya benzimidazole, ikoreshwa cyane mu kurwanya hepatiki ya Fasciola, kandi ifite ingaruka zigaragara zo kwica kuri Fasciola hepatica yimyaka itandukanye.fluke medicine.Umuti umaze kwinjizwa, ubangamira imiterere ya microtubule n'imikorere ya parasite, Irabuza irekurwa rya protease hydrolytic protease.Ingaruka za triclobendazole ku inyo ziratandukana hamwe nubunini, nkabantu bakuru bafite imbaraga nke (1 ~ 3μg / ml)
Ibiyobyabwenge biracyabaho amasaha 24, kandi ibikorwa biracika intege cyane murwego rwo hejuru (10-25μg / ml) mumasaha 24;ubwinshi bwa 25-50μg / ml irabuza rwose amasaha 24.Ariko cyane cyane inyo.Kuri 10 μg / ml, ibikorwa byamasaha 24 byose byarahagaritswe.
Imiti ya farumasi
Bioavailable ya triclobendazole ni ndende.Nyuma yo gutanga umunwa uburemere bwa mg / kg 10 mu ihene n'intama, imiti ya plasma ya plasma yageze kuri 15 μg / ml mu masaha 24 kugeza 36, kandi amaraso ya triclobendazole na metabolite yayo yari menshi.Agaciro ntarengwa k'ibiyobyabwenge karikubye inshuro 5 kugeza kuri 20 iyindi antenzmintique ya benzimidazole, kandi kurandura igice cyubuzima ni amasaha 22.Triclobendazole ahanini iba oxyde mu ntama n'imbeba kugeza kuri sulfone na sulfoxide, bihuza na albumin kandi bikomeza muri plasma iminsi irenga 7.Kwibanda cyane kwa plasma no guhuza plasma albumin bigaragara ko bifitanye isano nigihe kirekire cyibikorwa bya antifascioli.Nyuma yiminsi 10 yubuyobozi bwibiyobyabwenge mu ntama, hafi 95% yibiyobyabwenge bisohoka mu mwanda, 2% bisohoka mu nkari, naho munsi ya 1% bisohoka mu mata.
Ibikorwa no Gukoresha
Benzimidazole ibiyobyabwenge birwanya fasciola.Ikoreshwa cyane cyane mukurinda no kuvura indwara ya Fasciola hepatica yinka n'intama.
Ingaruka mbi
Nta reaction mbi yagaragaye iyo ikoreshejwe ukurikije imikoreshereze yagenwe
Kwirinda
(1) Abamugaye mugihe cyo gutanga amata.
(2) Nuburozi cyane kuroba, kandi ibikoresho bisigaye byibiyobyabwenge ntibigomba kwanduza isoko yamazi.
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(4) Gukaraba intoki nyuma yo gusaba
Igihe cyo gukuramo
Iminsi 56 y'inka n'intama
Ububiko
Bika ahantu munsi ya 30 ℃.
Hebei Veyong pharmaceutical Co., Ltd yashinzwe mu 2002, iherereye mu mujyi wa Shijiazhuang, Intara ya Hebei, mu Bushinwa, iruhande rw’umurwa mukuru wa Beijing.Ni ikigo kinini cyemewe na GMP cyemewe n’ibiyobyabwenge, hamwe na R&D, gukora no kugurisha amatungo ya APIs, imyiteguro, ibiryo byateganijwe hamwe ninyongeramusaruro.Nka Centre Tekinike yintara, Veyong yashyizeho uburyo bushya bwa R&D kumiti yubuvuzi bwamatungo, kandi nicyo kigo kizwi cyane mu guhanga udushya mu ikoranabuhanga rishingiye ku buvuzi bw’amatungo, hari abahanga mu bya tekinike 65.Veyong ifite ibishingwe bibiri: Shijiazhuang na Ordos, muri byo ikigo cya Shijiazhuang gifite ubuso bwa m2 78,706 m2, hamwe n’ibicuruzwa 13 bya API birimo Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, n'imirongo 11 yo gutegura harimo gutera inshinge, igisubizo cyo mu kanwa, ifu , premix, bolus, imiti yica udukoko hamwe na disinfectant, ects.Veyong itanga APIs, zirenga 100 bwite- label itegura, na serivisi ya OEM & ODM.
Veyong yita cyane ku micungire ya sisitemu ya EHS (Ibidukikije, Ubuzima & Umutekano), kandi yabonye impamyabumenyi ya ISO14001 na OHSAS18001.Veyong yashyizwe ku rutonde rw’inganda zigenda ziyongera mu Ntara ya Hebei kandi irashobora gutanga ibicuruzwa bikomeza.
Veyong yashyizeho uburyo bwuzuye bwo gucunga neza, yabonye icyemezo cya ISO9001, icyemezo cya GMP mu Bushinwa, icyemezo cya Ositarariya APVMA GMP, icyemezo cya Etiyopiya GMP, icyemezo cya Ivermectin CEP, kandi yatsinze igenzura rya FDA muri Amerika.Veyong ifite itsinda ryumwuga ryo kwiyandikisha, kugurisha na serivisi ya tekiniki, isosiyete yacu imaze kwiringira no gushyigikirwa nabakiriya benshi kubwiza bwibicuruzwa byiza, ubuziranenge bwiza mbere yo kugurisha na nyuma yo kugurisha, gucunga neza na siyansi.Veyong yakoze ubufatanye burambye n’inganda nyinshi zizwi cyane mu bya farumasi y’imiti n’ibicuruzwa byoherezwa mu Burayi, Amerika y'Epfo, Uburasirazuba bwo hagati, Afurika, Aziya, n'ibindi bihugu birenga 60.
