Tilipirosin
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Tilipirosin
Tilpipisin nubundi bwoko bushya bwa kimwe cya kabiri cya kabiri-kubarwa na macrol antibiyotike yinyamaswa, nikihe cya tylosin.
Ibikorwa bya farumasi
Ingaruka za Antibacteri ya Tilpironin isa na Tylosin, kandi ifite ingaruka zikomeye kubuza bagiteri-nziza ya bagiteri hamwe na bagiteri mbi nini. Uburyo bwa antibacialial ya Tilipirosiri ni kimwe na Macrolide. Irashobora guhuza hamwe na 50 subunit ya bagiteri ya ribose kugirango ibuza synthetesi yiminyururu ya peptiprotein, bityo ikagira ingaruka kumisozi ya peptide, bityo ikagira ingaruka kuri synthesis ya poroteine za bangateri. Imikoranire y'ibice bibiri bya piparidine idasanzwe kuri Tilipironin itandukanya uburyo bw'iki giti cya Tylosin na Tilconine, yerekeza i Lumeni kugira ngo ibangamire mukurangiyo.
Kuberako Tediroxine ifite amatsinda 3 yibanze amino, irashobora gukora impapuro zitandukanye zishishikarizwa mubihe bitandukanye. Umubare w'igihugu ni ikintu cy'ingenzi cyo gusenya ibikesha bya Lipide ya bagiteri kandi byinjira mu ntangiriro z'inyuma za bagiteri za gikabije, bityo ibikorwa bibi bya gildiostatic muri Vitro bigira ingaruka cyane na PH. Mu bihe bya acide, itsinda rya amino rirabyitwayemo, rikaviramo kugabanuka mu bikorwa bya Antibacterial ya Tediroxine, mu gihe hashyizweho ibikorwa bikomeye, bifite ibikorwa bya antibacteri.
Macrolide ibuza gusohora Cytokine proinflammatory, ibikorwa bya fosislipase, hamwe na Lekokone Tediroxine igabanya abahuza b'ibishishwa mugihe cyatewe na setike cyangwa imihangayiko.
Kugaragaza
Tilpirosine igira ingirakamaro kuri bagiteri za pathogenic zitera indwara zubuhumekero mu ngurube n'inka (nka pasteurella Multocisep, Limiteslla BrouropNetica, Bordeim Brousiseptica, Bordeim Brouseptica, Bordeim Brouseptica, Bordeim Brousisep, Lipmoim Sppruumerica, Bordeim Sprisin yabaye inshuro 2-32 kurenza iyo ya tilconin, hamwe nibikorwa bya antibacteri na escherichia coli byari byiza kuruta tylosin na tilconin. Nukuri kandi kuri mycoplasma, Spirochetes, Brucella, nibindi. Ubushakashatsi bwerekanye ko Terdexicous ngaruka ya parasuumeri na Florfebicol, ariko bakomeye bagiteri TilipisIn ni bagiteri muri bagiteri zimwe (nka Haemofilius parasus na actinobacill PleuropNenoniae), mugihe ari bagiteri cyane kuri bagiteri (nka pasteurella Multocida). Kubanga mu nda, hamwe no kugabanuka kwa PH agaciro (kuva 7.3 kugeza 6.7), Miripironin yarwanyaga Salmonella Eremoitidis na Escheichia Coli barashobora kwiyongera guhera saa kumi n'ebyiri ~ 25 ~ 256UB / ML. Kubwibyo, ingaruka za PH impinduka muri Vivo zigomba gusuzumwa mugihe ukora mu kizamini cya ViopisIn. Byongeye kandi, Mic ya Tilipirosin yarwanyaga indwara zisanzwe za Pasteurella Multocida yari 0.5Ug / ML muri Serum, yari ifite inshuro 0.25 munsi ya vitro, ishobora kuba ifitanye isano na serumu.
Enterococcus-IntereRoCoccus inka zamata irwanya cyane Tediroxine. TilipisIn ntabwo yumvaga Pasteurella Multocida na ManNheimia Haemolytictic bitwaye gen Mutant. Mu buryo nk'ubwo, mu buryo bushingiye ku ruganda rwa M. Bovis barwanya antibiyotike ya macrolide harimo nogipirosi. Imigenzo imwe n'imwe ya parasuilus parasuis nayo yasanze bisanzwe irwanya Tediroxine. Mycoplasma Bovis arashobora kubona vuba igisipironi, ariko kubera iterambere ryiburasirazuba bwa Mycoplasma, mubizamini bya vitro bishobora gutinda kuvurwa. Ubushakashatsi bwerekanye ko domaine II (Nucleotide 748) na domaine v (ihinduka muri nucleides 2059 na 2060) zifitanye isano no kongera kurwanya Macrolidi. Kubwibyo, ubwitonzi bwa M. Bovis kugirango ibiyobyabwenge birashobora kuboneka byihuse kubizamini bya molekolar yiyi mutation.
Ibirimo
98%
Ibisobanuro
Standard
Hebei Veyong Faormaceutical Co, Ltd, yashinzwe mu mujyi wa Shijiazhuang, Intara ya Hebei, Ubushinwa, iruhande rw'umurwa mukuru weijing. Ni uruganda runini rwa GMPE CMPS CYIZA, hamwe na R & D, umusaruro no kugurisha amatungo azwi, imyiteguro, amabwiriza ya Premix, agaburira abakyod. Nkikigo cya tekiniki cyintara, Vosong yashyizeho gahunda yo guhanga udushya ya R & D ibiyobyabwenge bishya byamatungo, kandi ni ingenzi mu gihangane ikora ibihangano by'ikoranabuhanga, hari abanyamwuga 65 tekinike. VOYON ifite ibishishwa bibiri: Shijiazhuang na Ordos, muri yo imirongo ya shijiazhuang ikubiyemo ubuso bwa 78.706. Kudatangara, Udukoko. Veyng itanga APIS, imyiteguro zirenga 100- yatangajwe na OEM & ODM.
Siyong yahagurukiye akamaro ka EHS (ibidukikije, ubuzima & umutekano), kandi yabonye Iso14001 na Ohsas1800 impamyabumenyi. VOYON yashyizwe ku rutonde rw'inganda zigaragara mu ntara ya Hebei kandi zishobora kwemeza ko ibicuruzwa bikomeza.
Veyng yashyizeho uburyo bwuzuye bwo gucunga ubuziranenge, yabonye icyemezo cyuzuye, Icyemezo cya Iso9001, Ositopiya GMPma, icyemezo cya Etiyopiya VOYON ifite itsinda ryumwuga wo kwisuzumisha, Serivise ya Desige, isosiyete yacu yarushijeho kwishingikiriza kandi igafasha abakiriya benshi bafite ubuziranenge bwibicuruzwa byiza, imiyoborere myiza, ubumenyi nubusanzwe. VOYON yakoze ubufatanye bwigihe kirekire hamwe nibigo byinshi bizwi ku rwego mpuzamahanga hamwe nibicuruzwa byoherejwe mu Burayi, Amerika y'Epfo, Uburasirazuba bwo hagati, Afurika, Aziya, n'ibindi.
